Lipid oxidation induces structural changes in biomimetic membranes

André Schröder — Wed, 01 Jan 2014 12:21:40 +0000

Soft Matter, 10, 4241-4247 (2014) G. Weber, T. Charitat, M. S. Baptista, A. F. Uchoa, C. Pavani, H. C. Junqueira, Y. Guo, V. A. Baulin, R. Itri, C. M. Marques, A. P. Schroder Oxidation can intimately influence and structurally compromise the levels of biological self-assembly embodied by intracellular and plasma membranes. Lipid peroxidation, a natural metabolic outcome of life with oxygen under light, is also a salient oxidation reaction in photomedecine treatments. However, the effect of peroxidation on the fate of lipid membranes remains elusive. Here we use a new photosensitizer that anchors and disperses in the membrane to achieve spatial

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ESR7-S: Optical microscopy and microrheology of giant unilamellar vesicles interacting with nano-objects

André Schröder — Thu, 05 Dec 2013 15:09:11 +0000

Experimental investigation of unilamellar vesicles and their dynamics Description Experimental project on the morphological and mechanical changes in lipid vesicles caused by exposure to the nano-objects, by means of epi- and confocal fluorescence studies. Emphasis will be put on understanding the influence of lipid composition, oxidation and investigating the membrane structure changes using ratiometric fluorescent probes. Starting date December 2014 Methods and techniques Related research topics

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