Jens-Uwe Sommer

Dresden: courses on general polymer theory and simulation

Jens-Uwe Sommer — Wed, 02 Sep 2015 19:18:01 +0000

13 April 2016. Core training courses will cover such topics as methodology, models, and statistical estimation and hypothesis tests. Essential background and computational models for modelling lipid bilayers and their interactions with nano-objects will also be provided. Given the large differences in background between experimental and theoretical/computational ESRs, training courses will aim to highlight these two areas at different levels. Compact courses on general polymer theory and simulation Open for all ESRs and ERs. ERs are included in tutorials and course preparation activities. ESRs can be involved into existing programs such as the Dresden International Graduate School for Biomedicine and Bioengineering DIGS-BB.

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ESR4-D: Molecular dynamics simulations of lipid bilayers and their interactions with nano-objects

Jens-Uwe Sommer — Thu, 05 Dec 2013 14:50:55 +0000

Theoretical physics, theory in soft matter, computer simulations Contact Chanfei Su Objectives The challenge of this project is to understand the role of molecular properties of self-organized phosphor-lipid bilayers on the interaction behaviour with nano-objects such as spherical nanoparticles, stiff rods and protein-like copolymers: Implementing an appropriately coarse-grained model for bilayer membranes based on highly parallelized LAMPS-code. Dynamics of lipids and extension to multi-component membranes consisting of lipids and cholesterol-like molecules. Analysing the effects of charge and stiffness of lipids on the effective interaction potentials with nano-objects. Understanding the influence of nano-objects on permeation, rupture and pore-formation. Tasks and methodology Implementing

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ESR3-D: Monte Carlo simulations of lipid membranes and their interactions with copolymers

Jens-Uwe Sommer — Thu, 05 Dec 2013 14:48:06 +0000

Theoretical physics, theory in soft matter, computer simulations Contact Ankush Checkervarty Objectives The challenge of this project is to rationalize the inter effective interactions between amphiphilic copolymers and self-organized lipid bilayer membranes using coarse-grained Monte Carlo methods: Analyze the effect of many copolymers interacting with a fluctuating membrane Finding copolymer sequences which match particular tasks such as increasing permeation or disruption Simulating membranes with internal stiffness to understand the role of phases in membrane-polymer-interactions Tasks and methodology Implementing simulation methods (BFM) for membrane-polymer systems based on existing framework and using GPU-code. Using evolutionary methods to search for optimal copolymer sequences. Developing

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