Kewin Ward

Biopharma: Freeze Drying – A Practical Guide to Process Development

Kevin Ward — Wed, 29 Jun 2016 17:34:46 +0000

20th – 21st September 2016. Freeze drying experts at Biopharma present a two-day course on the science and practice of developing products and processes for freeze drying. 21 September 2016 09.00 Welcome & Course Opening 09.15—10.00 Introduction to Freeze Drying Technology. The advantages and challenges of freeze drying. 10.00—10.40 Product Freezing. How ice structure and solute behaviour can affect freeze drying. Break 11.00—11.45 Primary Drying. The vapour pressure differential; balancing heat and pressure for optimal drying. 11.45-12.30 General Concepts of Formulation. Benefits and drawbacks of different excipients and issues affecting usage. Lunch (included) 13.30-14.00 Formulation Characterization (1). Use of freeze drying microscopy for determination

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ER2-B: Investigation of membrane permeating materials in biostabilisation

Kevin Ward — Thu, 05 Dec 2013 15:53:59 +0000

Experimental methods and characterisation techniques in cell preservation and biostabilisation Objectives Evaluate how size, shape and physical nature (net charge, pH responsiveness and nanoparticle and CNT characteristics) affect their interaction with membranes. These studies aim to link transfection efficiency from different therapeutic models (size, charge and proteins versus DNA) with the structural design of the therapeutic nanoparticles, and to shed more light on the toxicity of such substances in general. Tasks and methodology Testing new pH-responsive synthetic polymers (from Cambridge) to deliver (chemo-)biotherapeutics and stabilisers to the cell cytoplasm by disrupting endosomal membranes, which are used for cell preservation technology.

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