Smart Nano-objects for Alteration of Lipid bilayers (SNAL) Initial Training Network is a multidisciplinary EU-funded 7th Framework Programme specially designed to provide scientific and transferable skill training and career development for early stage researchers and experienced researchers in the field of lipid research.

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Participate 6th Workshop on biomaterials, cell membranes and lipid bilayers 2017 Altafulla Spain See details

ER2-B: Investigation of membrane permeating materials in biostabilisation

Experimental methods and characterisation techniques in cell preservation and biostabilisation

Objectives

Evaluate how size, shape and physical nature (net charge, pH responsiveness and nanoparticle and CNT characteristics) affect their interaction with membranes. These studies aim to link transfection efficiency from different therapeutic models (size, charge and proteins versus DNA) with the structural design of the therapeutic nanoparticles, and to shed more light on the toxicity of such substances in general.

Tasks and methodology

Testing new pH-responsive synthetic polymers (from Cambridge) to deliver (chemo-)biotherapeutics and stabilisers to the cell cytoplasm by disrupting endosomal membranes, which are used for cell preservation technology.

Starting date

September 2014

Related research topics

    Martin Stefanic

    MSCA Experienced Researcher at Biopharma, UK Investigation of membrane associating polymers, therapeutic nanoparticles and cell preservation experiments more...
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