Dates: 22nd-24th September 2015
Location: Horsley Park (Ockham Road South, East Horsley, KT24 6DT)
Lipid membranes are the basic building blocks for almost all living organisms. For years numerous reports have been focused on this area to establish a comprehensive understanding of membrane structures. More recently, the development of modern experimental techniques, such as small-angle X-ray scattering, small-angle neutron scattering and cyro-TEM, provides more powerful tools for this study. In addition to experimental study, theoretical models and computational simulations also contribute to broadening the scope of this field. The fundamental study of lipid membranes facilitates technical applications, for instance, designing drug carriers which can be transferred across membranes. To facilitate interdisciplinary co-orporations, it is necessary to organise lectures for researchers with different backgrounds but having the same interests in lipid membranes.
The lectures will focus on fundamentals and applications of lipid membranes with deep insights into the membrane biophysics. This will include an understanding of elasticity, membrane dynamics, phases and energetics and basic knowledge of measurement and simulation techniques. In addition, this topic will be extended to some practical applications which involve the interactions between nano-objects and lipid membranes. Such applications include drug delivery into the cell, cryo-preservation and toxicological response. The lectures will be given by experts in these areas, including some Investigators from within the SNAL network.
AUDIENCE AND VENUE
- All PhD students and postdocs are welcome to join these lectures.
- No registration fee is required. (The accommodation fee is to be covered by each delegate, £220 pp).
- The course will be held at Horsley Park, a splendid hotel within easy reach of London with picturesque views and modern facilities.
- The maximum number of attendees is 100 (due to the capacity of the venue).
9:00-12:00 Delegates arrival
12:00-13:30 Lunch and registration/ PIs management meeting
13:30-14:30 Continuum Theory of Lipid Membranes
Dr. Halim Kusumaatmaja, Durham University
14:30-15:30 Small-angle X-ray Scattering from Membranes
Dr. Nick Brooks, Imperial College London
15:30-16:00 Coffee Break
16:00-17:00 Determining of membrane properties using Neutron methods: SANS and Neutron Reflectivity
Dr. Ian Tucker, Unilever
17:00-18:00 Applications of Lipid Membrane Biophysics: Personal Care and Skin
Dr. Massimo Noro, Unilever
18:00-20:00 Poster Session*/ PIs management meeting
20:00-22:00 Formal Dinner
9:00-10:00 From membrane biology to membrane physics
Dr. Pietro Cicuta, University of Cambridge
10:00-11:00 The MechanoChemistry of Lipid Bilayer Membranes
Prof. David Needham, University of Southern Denmark
11:00-11:30 Coffee Break
11:30-12:30 Simulation of Lipid Membranes
Dr. Miguel Angel Gonzalez Gonzalez, Imperial College London
12:30-14:00 Lunch / PIs management meeting
14:00-15:00 Applications of Lipid Membrane Biophysics: Drug Delivery
Prof. Nigel Slater, University of Cambridge
15:00-16:00 Applications – Preservation of Red Blood Cells: Where Membrane Complexity and Physicochemical Process Dynamics Meet
Dr. Kevin Ward, Biopharma
16:00-18:00 Short research update presentations
18:00-20:00 Delegates activity / PIs management meeting
20:00-22:00 Dinner, Social event
8:00-10:00 Breakfast and greetings
*Posters will be shown in the hotel hall throughout the course. Discussions and brainstormings are strongly encouraged.
- Prof. John M. Seddon, Imperial College London
- Prof. Fernando Bresme, Imperial College London
- Dr. Rongjun Chen, Imperial College London
Local Organizing committee:
- Influence of a pH-sensitive polymer on the structure of monoolein cubosomes - 05/01/2018
- pH-Responsive, Lysine-Based, Hyperbranched Polymers Mimicking Endosomolytic Cell-Penetrating Peptides for Efficient Intracellular Delivery - 09/05/2017
- Membrane-Anchoring, Comb-Like Pseudopeptides for Efficient, pH-Mediated Membrane Destabilization and Intracellular Delivery - 27/02/2017