Permeability of lipid bilayers induced by polymers

Lipid bilayers emerge by self-organization of amphiphilic molecules and are the essential component of membranes of living cells. An important task of them is the selective exchange of substances between the cell and its environment. This becomes particularly interesting for delivering foreign molecules and RNA into the cell. In the classical view of cell biology static structures such as pores and channels formed by specific proteins control the translocation of molecules. In this work we show that there exists a straight forward mechanism for translocation of polymers through lipid bilayers if the monomers of the chain show a certain balance of hydrophobic and hydrophilic strength.

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Vladimir Baulin

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