Smart Nano-objects for Alteration of Lipid bilayers (SNAL) Initial Training Network is a multidisciplinary EU-funded 7th Framework Programme specially designed to provide scientific and transferable skill training and career development for early stage researchers and experienced researchers in the field of lipid research.

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Association of polymers and small solute molecules with phospholipid membranes

Theoretical physics, theory in soft matter, computer simulations

Protein insertion into bilayer


In many cases the properties of cell membranes are modified through biopolymers and small solute molecules such as anesthetics or neurotransmitters. They can associate to membranes and significantly alter their structure, either thermodynamic state or induce reorganization in form of pores. The project aims to describe the fundamental controls of these processes that trigger such membrane modification or structural reorganization using the Single Chain Mean Field (SCMF) theory.

Tasks and methodology

  • Implementation of a hybrid Single Chain Mean Field theory with Monte Carlo simulations
  • Construction of the models for polymer – bilayer interactions

Starting date

October 2012

Related research topics

Yachong Guo

Research student at the Universitat Rovira i Virgili, Tarragona, Spain Theory and simulations of small solute molecules and their interactions with lipid membranes, more...
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