Smart Nano-objects for Alteration of Lipid bilayers (SNAL) Initial Training Network is a multidisciplinary EU-funded 7th Framework Programme specially designed to provide scientific and transferable skill training and career development for early stage researchers and experienced researchers in the field of lipid research.

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Participate 6th Workshop on biomaterials, cell membranes and lipid bilayers 2017 Altafulla Spain See details

Membrane-active block-copolymers

Computer simulations can suggest physical principles of the mechanism of action, optimal architectures of synthetic polymers. These structures can then be synthesized and tested by numerous experimental techniques. (10.1039/c2sm26008e),(10.1209/0295-5075/98/18003)

block copolymer

A key challenge for the project is the design and synthesis of novel polymeric biomaterials able to modify membrane properties.

Particular focus of the project

  • Membrane-attaching polymers
  • Polymers enhancing permeability of lipid bilayers
  • Polymers translocating through membranes
  • Pore-forming polymers

Associated projects

  • Association of polymers and small solute molecules with phospholipid membranes

    Theoretical physics, theory in soft matter, computer simulations Objectives In many cases the properties of cell membranes are modified through biopolymers and small solute molecules such as anesthetics or neurotransmitters. They can associate to membranes and significantly alter their structure, either thermodynamic state or induce reorganization in form of pores. The project aims to describe the fundamental ...

  • ESR2-T: Molecular simulation models of biomimetic polymers in lipid bilayers

    Theoretical physics, theory in soft matter, computer simulations Contact Adrien Berthault Objectives The aim of this project is to understand the interactions of lipid membranes with nano-objects including functional biomimetic polymers, polymeric micelles, carbon nanotubes and polymer therapeutic complexes/conjugates to enable the intelligent design of novel materials with improved bilayer modifying properties. A full range of theoretical methods will be ...

  • ESR1-T: Computer simulations of equilibrium structures of lipid membranes and nano-objects

    Theoretical physics, theory in soft matter, computer simulations Contact Berardo Manzi Objectives The aim of this project is to understand the interactions of lipid membranes with nano-objects including functional biomimetic polymers, polymeric micelles, carbon nanotubes and polymer therapeutic complexes/conjugates to enable the intelligent design of novel materials with improved bilayer modifying properties. A full range of theoretical methods will be ...

Outreach activities

    Work in progress.

SNAL publications

    Work in progress.

Project team

Yachong Guo

Research student at the Universitat Rovira i Virgili, Tarragona, Spain Theory and simulations of small solute molecules and their interactions with lipid membranes, more...
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Vladimir Baulin

Universitat Rovira i Virgili (URV), Tarragona, Spain


Coordinator of SNAL network. Expertise is computer simulations and theory of soft matter systems. Research is focused on the topics in the theory of Soft matter, polymer physics. more...

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Berardo Mario Manzi

MSCA Early Stage Researcher at the Universitat Rovira i Virgili, Tarragona, Spain Theory and simulations of interaction of nano-objects with lipid membranes. more...

Ankush Checkervarty

MSCA Early Stage Researcher at Institut für Polymerforschung Dresden, Germany. Molecular Carlo simulations of lipid membranes more...

Adrien Berthault

MSCA Early Stage Researcher at the Universitat Rovira i Virgili, Tarragona, Spain Theory and simulations of interaction of nanoobjects with lipid membranes, more...

Latest posts by Adrien Berthault (see all)

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